A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...

Heart failure often develops after a heart attack because excessive collagen-based scar tissue forms during repair. While collagen is necessary to reinforce scars, disease and chronic inflammation can ...

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have identified new inhibitors of the enzyme human 15-lipoxygenase-2 (h15-LOX-2 ...

In vitro experiments show juglone, a naphthoquinone from walnut green husks, potently and competitively inhibits the human ...

Researchers at Nagoya University have identified BCAT1, an enzyme involved in proline supply for collagen synthesis, as a ...

A research team led by Dr. Martin Mollenhauer from the Heart Center at University Hospital Cologne has investigated the link between obesity and the risk of cardiovascular disease in greater detail.

An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment ...

First publication reveals how roginolisib uniquely locks the cancer-driving enzyme PI3Kδ in an inactive state, differentiating the drug from ...

α-Glucosidase is a key enzyme in the final step of carbohydrate digestion, cleaving terminal glucose residues from oligosaccharides at the intestinal brush border. Inhibition of this enzyme delays ...

A new review in Plant Molecular Biology defines plant multifunctional inhibitors as a distinct class of double-headed defense ...