The subthalamic nucleus contains subpopulations with different contributions to deliberative decision-making based on noisy evidence and reward-driven preferences.

Findings suggest placental mammals that lived in China following the most recent mass extinction evolved large teeth before developing more specialized dental structures associated with different ...

Keratinocytes, which activate an EMT-like program in the skin, can prevent melanoma invasion, highlighting how changes in the tumor microenvironment can act as restraining forces in cancer.

Desert Hedgehog signaling promotes stem Leydig cell differentiation through a Ptch2-Gli1-Sf1 regulatory axis in Nile tilapia.

Fine-scale exogenous attention within the foveola selectively enhances contrast gain at low-to-mid spatial frequencies while increasing response gain across a broad spatial frequency range.

Metabolic dysfunction-associated steatotic liver disease (MASLD) progression involves the replacement of protective embryo-derived Kupffer cells (KCs) by inflammatory monocyte-derived macrophages ...

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.

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The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

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