Keratinocytes, which activate an EMT-like program in the skin, can prevent melanoma invasion, highlighting how changes in the tumor microenvironment can act as restraining forces in cancer.

Findings suggest placental mammals that lived in China following the most recent mass extinction evolved large teeth before developing more specialized dental structures associated with different ...

Dissecting protective versus detrimental immune responses uncovers biomarkers and mechanisms that can inform the rational design and evaluation of live attenuated vaccines against African swine fever ...

The subthalamic nucleus contains subpopulations with different contributions to deliberative decision-making based on noisy evidence and reward-driven preferences.

Metabolic dysfunction-associated steatotic liver disease (MASLD) progression involves the replacement of protective embryo-derived Kupffer cells (KCs) by inflammatory monocyte-derived macrophages ...

A review of literature regarding trained immunity (TI) differentiates two distinct stages of metabolic immune regulation, with primary metabolic changes influencing early epigenetic adaptations that ...

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Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and ...

An initial genome-wide analysis sheds light on Faroese ancestry and recent selection, and lays a foundation for understanding the genetics behind health and disease within this population.

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.

Fine-scale exogenous attention within the foveola selectively enhances contrast gain at low-to-mid spatial frequencies while increasing response gain across a broad spatial frequency range.

Long-term motor recovery after musculoskeletal alteration relies on gradually developing novel compensatory movements to overcome the rigid, maladaptive timing of stable muscle synergies.